function:Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen.,induction:By heat shock.,polymorphism:A functional SNP in the promoter of SERPINH1 is associated in African Americans with an increased risk for preterm premature rupture of membranes (PPROM) [MIM:610504]. PPROM is defined as rupture of the membranes before 37 weeks of gestation. SERPINH1 with the -656 T allele displays significantly reduced promoter activity compared to the major -656 C allele. Prematurity is correlated with an increased frequency of the -656 T allele.,similarity:Belongs to the serpin family.,
Endoplasmic reticulum lumen.
Brain,Cartilage,Fibroblast,Ovary,Periodontal ligament,Skin,
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