domain:Contains a death domain involved in the binding of RIP protein.,domain:The CARD domain mediates the interaction with caspase-2.,function:Apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruites caspase-2 to the TNFR-1 signalling complex.,similarity:Contains 1 CARD domain.,similarity:Contains 1 death domain.,subunit:Interacts with LRDD.,tissue specificity:Constitutively expressed in most tissues, with particularly high expression in adult heart, testis, liver, skeletal muscle, fetal liver and kidney.,
Cytoplasm . Nucleus .
Constitutively expressed in most tissues, with particularly high expression in adult heart, testis, liver, skeletal muscle, fetal liver and kidney.
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