developmental stage:Transcript peaks at G1-S transition, but total protein remains constant throughout the cell cycle. Expressed in multiple tissues during embryogenesis, including neural crest-derived structures.,function:Required for initiation of chromosomal DNA replication.,similarity:Belongs to the CDC45 family.,subunit:Associated with ORC2L.,tissue specificity:Widely expressed, highest levels are found in adult testis and tyhmus and in fetal liver.,
Cytoplasm. Nucleus.
Widely expressed, highest levels are found in adult testis and thymus and in fetal liver.