disease:Mutations in the promoter region of NFKBIL1 represent the second rheumatoid arthritis susceptibility locus within the HLA region [MIM:180300].,function:May be a negative regulator of NF-kappa-B activation.,similarity:Contains 2 ANK repeats.,tissue specificity:Detected in different cell types including monocytes, T-cells, B-cells and hepatocytes.,
Nucleus . Nuclear localization with a speckled expression pattern in some cells. Colocalizes with CACTIN in the nucleus.
Detected in different cell types including monocytes, T-cells, B-cells and hepatocytes.
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