function:May act as scaffold protein (By similarity). May play a role in the development of the retina. Has been suggested to play a role in axon guidance.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 HP (headpiece) domain.,similarity:Contains 2 LIM zinc-binding domains.,similarity:Contains 4 LIM zinc-binding domains.,subcellular location:Associated with the cytoskeleton.,subunit:Binds F-actin. Interacts with ABRA.,tissue specificity:Detected in liver, heart, skeletal muscle, brain and retina, where it is concentrated in the inner segment and in the outer plexiform layers.,
Cytoplasm . Cytoplasm, cytoskeleton . Associated with the cytoskeleton. .
Detected in liver, heart, skeletal muscle, brain and retina, where it is concentrated in the inner segment and in the outer plexiform layers.