catalytic activity:An aldehyde + NAD(P)(+) + H(2)O = an acid + NAD(P)H.,function:Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Seems to be the key enzyme in the formation of an RA gradient along the dorso-ventral axis during the early eye development and also in the development of the olfactory system.,pathway:Cofactor metabolism; retinol metabolism.,similarity:Belongs to the aldehyde dehydrogenase family.,tissue specificity:Expressed at low levels in many tissues and at higher levels in salivary gland, stomach, and kidney.,
Cytoplasm .
Expressed at low levels in many tissues and at higher levels in salivary gland, stomach, and kidney.
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