function:May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1).,induction:Down-regulated in cancer pancreatic cells undergoing differentiation and apoptosis.,similarity:Belongs to the vinculin/alpha-catenin family.,subunit:Interacts with ARHGEF1.,tissue specificity:Widely expressed. Expressed at lower level in neural tissues and at the highest level in the adrenal gland.,
Cytoplasm, cytoskeleton . Cell membrane ; Peripheral membrane protein .
Widely expressed. Expressed at lower level in neural tissues and at the highest level in the adrenal gland.
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