domain:Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).,function:Forms a water-specific channel that participates in distinct physiological functions such as glomerular filtration, tubular endocytosis and acid-base metabolism.,similarity:Belongs to the MIP/aquaporin (TC 1.A.8) family.,
Cytoplasmic vesicle membrane ; Multi-pass membrane protein .
Kidney,Testis,
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