domain:Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).,function:Forms a water-specific channel; mercury-sensitive. Not permeable to glycerol or urea.,similarity:Belongs to the MIP/aquaporin (TC 1.A.8) family.,tissue specificity:Expressed only in pancreas and colon.,
Mitochondrion membrane ; Multi-pass membrane protein .
Detected in the sperm midpiece (at protein level) (PubMed:28042826). Expressed only in pancreas and colon.