developmental stage:Expressed in fetal tissues with higher expression in fetal heart and kidney.,function:May play a role in monocyte differentiation and lipid homeostasis.,induction:Up-regulated during monocyte differentiation into macrophages. Down-regulated by cholesterol loading of macrophages.,similarity:Belongs to the ABC transporter family. ABCA subfamily.,similarity:Contains 2 ABC transporter domains.,tissue specificity:Widely expressed with higher expression in heart.,
Membrane ; Multi-pass membrane protein .
Widely expressed with higher expression in heart.
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