B3GT6 Polyclonal Antibody

catalytic activity:UDP-galactose + 4-beta-D-galactosyl-O-beta-D-xylosylprotein = UDP + 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein.,caution:PubMed:9892646 describes the wrong protein; the cDNAs used had been switched inadvertently.,cofactor:Manganese.,function:Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-linked galactose residue. Has a preference for galactose-beta-1,4-xylose that is found in the linker region of glycosaminoglycans, such as heparan sulfate and chondroitin sulfate. Has no activity towards substrates with terminal glucosamine or galactosamine residues.,online information:Beta-1,3-galactosyltransferase 6,online information:GlycoGene database,pathway:Glycan metabolism; chondroitin sulfate biosynthesis.,pathway:Glycan metabolism; heparan sulfate biosynthesis.,similarity:Belongs to the glycosyltransferase 31 family.,tissue specificity:Ubiquitous.,