function:May play an important role in heart development.,similarity:Belongs to the popeye family.,tissue specificity:Expressed in fetal and adult heart and skeletal muscle.,
Lateral cell membrane . Cell junction, tight junction . Membrane ; Multi-pass membrane protein . Cell membrane, sarcolemma . Membrane, caveola . Colocalizes with VAMP3 at the cell-cell contact in cardiac and skeletal muscle (By similarity). Its movement from the cytoplasm to membrane is an early event occurring concurrently with cell-cell contact. Colocalizes in epithelial cells with OCLN and TJP1 in an apical-lateral position within the z axis. Detected at cell-cell contact but never observed at the free surface of epithelial cells. .
Expressed in epithelial cells (at protein level). Expressed in fetal and adult heart and skeletal muscle.