developmental stage:Expression of isoform 1 increases throughout the cell cycle and peaks in G2/M phase. Expression of isoform 2 is highest in G1 phase and decreases thereafter.,function:May play a role in cell-cycle-dependent microtubule organization.,PTM:Phosphorylated. Phosphorylation increases in colcemide-treated cells.,subcellular location:Associated with mitotic spindles.,tissue specificity:Detected in testis.,
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole . Associated with mitotic spindles.
Expressed in adult and fetal brain with enrichment in the cerebellum. Detected in testis.
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