function:The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.,mass spectrometry:This is the measured mass for the GINS complex PubMed:17557111,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the GINS2/PSF2 family.,subunit:Component of the GINS complex which is a heterotetramer of GINS1, GINS2, GINS3 and GINS4. Forms a stable subcomplex with GINS3. GINS complex interacts with DNA primase in vitro.,
Nucleus . Chromosome . Associates with chromatin. .
Brain,Dendritic cell,Umbilical cord blood,
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