domain:Contains a protease-associated domain (PA) of unknown function.,function:Involved in endoplasmic reticulum-associated degradation (ERAD). Accelerates the glycoprotein ERAD by proteasomes. This process depends on mannose-trimming from the N-glycans. Seems to have alpha 1,2-mannosidase activity.,PTM:N-glycosylated.,similarity:Belongs to the glycosyl hydrolase 47 family.,similarity:Contains 1 PA (protease associated) domain.,
Endoplasmic reticulum lumen .
Brain,Liver,Lung,Placenta,Testis,Whole embr
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