function:Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.,similarity:Belongs to the argonaute family. Ago subfamily.,similarity:Contains 1 PAZ domain.,similarity:Contains 1 Piwi domain.,subunit:Interacts with EIF4B, IMP8, PRMT5 and TNRC6B.,
Cytoplasm, P-body .
Placenta,Testis,
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