catalytic activity:ATP + H(2)O = ADP + phosphate.,cofactor:Magnesium.,function:May regulate osteoblast proliferation and differentiation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the AAA ATPase family.,subunit:Hexamer.,
Nucleus . Cytoplasm . Cytoplasm, perinuclear region . Together with RAD51 and a subset of H2A histone proteins, redistributed in discrete nuclear DNA damage-induced foci after ionizing radiation (IR) treatment (PubMed:23754376).
Ovary,Pancreas,Skin,Testis,
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