PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 6 Kelch repeats.,
Cytoplasm . Cytoplasm, cytoskeleton, spindle . Predominantly in mitotic cells. Localized diffusely in the cytoplasm during the interphase. During metaphase is localized throughout the cell and more widely dispersed than the microtubules. In anaphase cells is localized between the two sets of separated chromosomes as well as at the spindle poles. During telophase is localized arround the nuclei of the two daughter cells. Not detected at the midbody region during cytokinesis.
Brain,Tongue,Uterus,