function:Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor.,similarity:Belongs to the LDLR family.,similarity:Contains 2 CUB domains.,similarity:Contains 5 LDL-receptor class A domains.,subunit:May interact with GNB2L1, MADHIP and ITGB1BP3.,tissue specificity:Widely expressed in heart, skeletal muscle, brain, lung, placenta and pancreas, but not in tissues consisting of a large number of epithelial cells, such as liver and kidney. Expressed at very low levels in a number of tumor-derived cell lines.,
Membrane ; Single-pass type I membrane protein . Membrane, coated pit .
Widely expressed in heart, skeletal muscle, brain, lung, placenta and pancreas, but not in tissues consisting of a large number of epithelial cells, such as liver and kidney. Expressed at very low levels in a number of tumor-derived cell lines.
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