LRP1B Polyclonal Antibody

function:Potential cell surface proteins that bind and internalize ligands in the process of receptor-mediated endocytosis.,miscellaneous:The gene is preferentially inactivated in one histological type of lung cancer (non-small cell lung cancer (NSCLC)). May thus play an important role in tumorigenesis of NSCLCs.,similarity:Belongs to the LDLR family.,similarity:Contains 14 EGF-like domains.,similarity:Contains 32 LDL-receptor class A domains.,similarity:Contains 36 LDL-receptor class B repeats.,subunit:Binds LRPAP1, PLAU, PLAT and SERPINE1; binding is followed by internalization and degradation of the ligands.,tissue specificity:Expressed in thyroid gland and in salivary gland, as well as in adult and fetal brain.,