IMP2L Polyclonal Antibody

disease:Defects in IMMP2L may be a cause of Gilles de la Tourette syndrome (GTS) [MIM:137580]. GTS is a neurologic disorder manifested particularly by motor and vocal tics and associated with behavioral abnormalities.,function:Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO.,similarity:Belongs to the peptidase S26 family.,similarity:Belongs to the peptidase S26 family. IMP2 subfamily.,subunit:Heterodimer of 2 subunits, IMMPL1 and IMMPL2.,tissue specificity:Expressed in all tissues tested except adult liver and lung.,