function:Cell adhesion glycoprotein which is widely distributed in basement membranes. Binds to collagens I and IV, to perlecan and to laminin 1. Does not bind fibulins. It probably has a role in cell-extracellular matrix interactions.,PTM:Highly N- and O-glycosylated.,similarity:Contains 1 NIDO domain.,similarity:Contains 1 nidogen G2 beta-barrel domain.,similarity:Contains 2 thyroglobulin type-1 domains.,similarity:Contains 5 EGF-like domains.,similarity:Contains 5 LDL-receptor class B repeats.,subunit:Interacts with LAMA2 (By similarity). Interacts with COL13A1.,tissue specificity:Heart, placenta and bone. Less in pancreas, kidney and skeletal muscle.,
Secreted, extracellular space, extracellular matrix, basement membrane.
Heart, placenta and bone. Less in pancreas, kidney and skeletal muscle.
下载说明书
