cofactor:Calcium.,function:May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.,online information:Scramblase entry,similarity:Belongs to the phospholipid scramblase family.,tissue specificity:Exclusively expressed in testis.,
Membrane ; Single-pass type II membrane protein .; [Isoform 1]: Nucleus .
Expression of isoform 1 seems restricted to testis.