function:Converts HDL into larger and smaller particles. May play a key role in extracellular phospholipid transport and modulation of hdl particles.,similarity:Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.,tissue specificity:Wide tissue distribution. Placenta > pancreas > lung > kidney > heart > liver > skeletal muscle > brain.,
Secreted . Nucleus . Nuclear export is XPO1/CRM1-dependent. .
Widely expressed. Highest level of expression in the ovary, thymus and placenta, with moderate levels found in the pancreas, small intestine, testis, lung and prostrate. Low level expression in the kidney, liver and spleen, with very low levels found in the heart, colon, skeletal muscle, leukocytes and brain. Expressed in the cortical neurons.
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