PABP4 Polyclonal Antibody

  • Catalog Number:
    RA04403
  • Size:
    40μL 100μL 200μL
  • Price:
    960 / 2300 / 3780 RMB(含税报价)
  • Form:
    Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Reactivity:
    Human ; Mouse ; Rat
  • Application:
    WB ELISA
功能
细胞定位
组织表达
function:Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo.,PTM:Arg-518 is dimethylated, probably to asymmetric dimethylarginine.,similarity:Belongs to the polyadenylate-binding protein type-1 family.,similarity:Contains 1 PABC domain.,similarity:Contains 4 RRM (RNA recognition motif) domains.,subunit:Interacts with NFX1.,tissue specificity:Expressed at low levels in resting normal T cells; following T-cell activation, however, mRNA levels are rapidly up-regulated.,
Cytoplasm . Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Expressed at low levels in resting normal T cells; following T-cell activation, however, mRNA levels are rapidly up-regulated.