function:Stimulates GDP/GTP exchange reaction of a group of small GTP-binding proteins (G proteins) including Rap1a/Rap1b, RhoA, RhoB and KRas, by stimulating the dissociation of GDP from and the subsequent binding of GTP to each small G protein.,similarity:Contains 5 ARM repeats.,
Cytoplasm, cytosol . Endoplasmic reticulum . Mitochondrion . Nucleus . Nuclear import is dependent on complexing with a GTPase containing a C-terminal polybasic region. .
Brain,Muscle,PCR rescued clones,Peripheral blood,
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