function:May act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS-mediated transformation.,similarity:Contains 1 dilute domain.,similarity:Contains 1 Ras-associating domain.,subcellular location:Associated with perinuclear vesicles. Is recruited to Golgi stacks by activated HRAS.,subunit:Interacts with Ras family members that have been activated by GTP binding. Interacts with HRAS, RAP1A, RAP2, RRAS, RAF1 and RRAS2.,tissue specificity:Highly expressed in heart. Detected at lower levels in placenta and pancreas.,
Cytoplasm, perinuclear region . Golgi apparatus, Golgi stack . Associated with perinuclear vesicles. Is recruited to Golgi stacks by activated HRAS.
Highly expressed in heart. Detected at lower levels in placenta and pancreas.
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