RSF1 Polyclonal Antibody

  • Catalog Number:
    RA04534
  • Size:
    40μL 100μL 200μL
  • Price:
    960 / 2300 / 3780 RMB(含税报价)
  • Form:
    Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Reactivity:
    Human ; Mouse ; Rat
  • Application:
    WB ELISA
功能
细胞定位
组织表达
alternative products:Experimental confirmation may be lacking for some isoforms,function:Required for assembly of regular nucleosome arrays by the RSF chromatin-remodeling complex. Facilitates transcription of hepatitis B virus (HBV) genes by the pX transcription activator. In case of infection by HBV, together with pX, it represses TNF-alpha induced NF-kappa-B transcription activation. Represses transcription when artificially recruited to chromatin by fusion to a heterogeneous DNA binding domain.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Contaminating sequence. Potential poly-A sequence starting in position 476.,similarity:Contains 1 DDT domain.,similarity:Contains 1 PHD-type zinc finger.,subunit:Interacts with SMARCA5/SNF2H to form the RSF complex. Also binds the HBV pX/HBx protein, which is required to activate transcription of the viral genome.,tissue specificity:Ubiquitously expressed.,
Nucleus . Localization is diffuse during mitosis (PubMed:12972596). Co-localizes with SMARCA5 in the nucleus (PubMed:12972596). .
Ubiquitously expressed. Highly expressed in the heart, skeletal muscle, kidney and placenta (PubMed:12972596). Expressed at low levels in the brain and colon (PubMed:12972596).