caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 Rho-GAP domain.,tissue specificity:Expressed in testis. Expressed at moderate level in kidney and ovary, and weakly expressed in spleen and skeletal muscle.,
nucleoplasm,cytosol,integral component of membrane,cell junction,
Expressed in testis. Expressed at moderate level in kidney and ovary, and weakly expressed in spleen and skeletal muscle.