NQO2 Polyclonal Antibody

catalytic activity:1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide + a quinone = 1-(beta-D-ribofuranosyl)nicotinamide + a hydroquinone.,cofactor:Binds 1 zinc ion per subunit.,cofactor:FAD.,enzyme regulation:Inhibited by melatonin, resveratrol and 5-hydroxytryptamine.,function:The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.,miscellaneous:Uses dihydronicotinamide riboside (NRH) rather than NAD(P)H as an electron donor.,similarity:Belongs to the NAD(P)H dehydrogenase (quinone) family.,subunit:Homodimer.,