function:Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.,similarity:Belongs to the transient receptor family. STrpC subfamily.,similarity:Contains 3 ANK repeats.,subunit:Interacts with TRPC3. Interacts with ITPR3. Interacts with MX1 and RNF24.,tissue specificity:Seems to be ubiquitous.,
Membrane; Multi-pass membrane protein.
Seems to be ubiquitous.