function:Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin.,similarity:Belongs to the potassium channel KCNN family.,subunit:Heterooligomer. The complex is composed of 4 channel subunits each of which binds to a calmodulin subunit which regulates the channel activity through calcium-binding.,
Membrane; Multi-pass membrane protein.
Fetal brain,Hippocampus,
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