domain:The ion transport-like region is related to the membrane segments of voltage-gated ion channels. Its function is unknown.,function:Sperm-specific sodium/hydrogen exchanger involved in intracellular pH regulation of spermatozoa. Required for sperm motility and fertility. Involved in sperm cell hyperactivation, a step needed for sperm motility which is essential late in the preparation of sperm for fertilization. Required for the expression and bicarbonate regulation of the soluble adenylyl cyclase (sAC).,similarity:Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.,similarity:Contains 1 cyclic nucleotide-binding domain.,subunit:Interacts with soluble adenylyl cyclase (sAC).,
Cell projection, cilium, flagellum membrane ; Multi-pass membrane protein .
Testis,
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