function:Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals.,miscellaneous:This protein is the target of psychomotor stimulants such as amphetamines or cocaine.,online information:Dopamine transporter entry,similarity:Belongs to the sodium:neurotransmitter symporter (SNF) family.,subunit:Homooligomer; disulfide-linked. Interacts with PRKCABP and TGFB1I1.,
Cell membrane ; Multi-pass membrane protein . Cell projection, neuron projection . Cell projection, axon . Localizes to neurite tips in neuronal cells (By similarity). Colocalizes with SEPTIN4 at axon terminals, especially at the varicosities (By similarity). .
Highly expressed in substantia nigra (PubMed:7637582). Expressed in axonal varicosities in dopaminergic nerve terminals (at protein level) (PubMed:17296554). Expressed in the striatum (at protein level) (PubMed:17296554).
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