function:DsDNA-dependent ATPase which acts as a transcription termination factor by coupling ATP hydrolysis with removal of RNA polymerase II from the DNA template. May contribute to mitotic transcription repression. May also be involved in pre-mRNA splicing.,similarity:Belongs to the SNF2/RAD54 helicase family.,similarity:Contains 1 helicase ATP-binding domain.,similarity:Contains 1 helicase C-terminal domain.,subcellular location:Cytoplasmic during interphase. Relocates to the nucleus as cells enter mitosis.,subunit:Interacts with CDC5L. Part of the spliceosome.,
Cytoplasm . Nucleus . Cytoplasmic during interphase. Relocates to the nucleus as cells enter mitosis.
Aorta endothelial cell,Brain,Epithelium,
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