catalytic activity:Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.,disease:Defects in PTPN12 are found in some colon cancers.,similarity:Belongs to the protein-tyrosine phosphatase family. Non-receptor class 4 subfamily.,similarity:Contains 1 tyrosine-protein phosphatase domain.,subunit:Interacts with TGFB1I1 (By similarity). Interacts with PSTPIP1.,
Cytoplasm . Cell junction, focal adhesion . Cell projection, podosome . Partial translocation to focal adhesion sites may be mediated by interaction with SORBS2. .
Brain,Cerebellum,Colon,Colorectal carcinoma,Epithel
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