function:Transcriptional activator. Binds the consensus sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR. Important for liver genes transcription.,online information:Hepatocyte nuclear factors entry,similarity:Belongs to the CUT homeobox family.,similarity:Contains 1 CUT DNA-binding domain.,similarity:Contains 1 homeobox DNA-binding domain.,subunit:Binds DNA as a monomer.,tissue specificity:Highly expressed in liver; lower expression in testis and skin.,
Nucleus.
Highly expressed in liver; lower expression in testis and skin.
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