KDM5D Polyclonal Antibody

  • Catalog Number:
    RA05094
  • Size:
    40μL 100μL 200μL
  • Price:
    960 / 2300 / 3780 RMB(含税报价)
  • Form:
    Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Reactivity:
    Human ; Mouse ; Rat
  • Application:
    WB ELISA
功能
细胞定位
组织表达
alternative products:Additional isoforms seem to exist,cofactor:Ascorbate.,cofactor:Fe(2+).,domain:The JmjC domain is required for enzymatic activity.,function:Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. May play a role in spermatogenesis.,similarity:Belongs to the JARID1 histone demethylase family.,similarity:Contains 1 ARID domain.,similarity:Contains 1 JmjC domain.,similarity:Contains 1 JmjN domain.,similarity:Contains 2 PHD-type zinc fingers.,subunit:Interacts with PCGF6.,
Nucleus .
Expression is highly down-regulated in metastatic prostate tumors.