function:Component of the origin recognition complex (ORC) that binds origins of replication. It has a role in both chromosomal replication and mating type transcriptional silencing. Binds to the ARS consensus sequence (ACS) of origins of replication in an ATP-dependent manner.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the ORC3 family.,subunit:ORC is composed of six subunits.,
Nucleus . Chromosome .
Brain,Liver,Testis,Uterus,
下载说明书
