disease:Most specific Hodgkin disease associated antigen.,function:Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B.,PTM:Phosphorylated on serine and tyrosine residues.,similarity:Contains 6 TNFR-Cys repeats.,subunit:Interacts with TRAF1, TRAF2, TRAF3 and TRAF5.,
[Isoform 1]: Cell membrane ; Single-pass type I membrane protein .; [Isoform 2]: Cytoplasm .
[Isoform 2]: Detected in alveolar macrophages (at protein level).
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