function:Plays a role in autophagy.,induction:By hypoxia, leading to inhibit NOS3 expression.,miscellaneous:ATG9B gene is located on the opposite DNA strand of the NOS3 gene at chromosome 7q36. The genes are oriented in a tail-to-tail configuration and the mRNAs encoding ATG9B and NOS3 are complementary for 662 nucleotides. ATG9B transcription may a role in NOS3 transcription regulation.,similarity:Belongs to the ATG9 family.,tissue specificity:Highly expressed in placenta (trophoblast cells) and pituitary gland. Not expressed in vascular endothelial.,
Preautophagosomal structure membrane ; Multi-pass membrane protein . Under amino acid starvation or rapamycin treatment, redistributes from a juxtanuclear clustered pool to a dispersed peripheral cytosolic pool (PubMed:18936157). The starvation-induced redistribution depends on ULK1 and ATG13 (PubMed:18936157). .
Highly expressed in placenta (trophoblast cells) and pituitary gland. Not expressed in vascular endothelial.
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