developmental stage:Expressed in primordial germ (PGC), embryonic germ (EGC) and embryonic stem (ESC) cells. Not detected in embryonic carcinoma (ECC) cells.,function:Involved in the maintenance of embryonic stem (ES) cell pluripotency. Dispensable for self-renewal of pluripotent ES cells and establishment of germ cells. Associates with specific target mRNAs.,induction:Down-regulated in differentiated embryonic stem (ESC) cells, compared with strong expression in undifferentiated ESC cells.,similarity:Belongs to the KHDC1 family.,similarity:Contains 1 KH domain.,
Cytoplasm .
下载说明书
