function:Cell surface proteoglycan that bears heparan sulfate.,PTM:This cell-associated glypican is further processed to give rise to a medium-released species.,similarity:Belongs to the glypican family.,
Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side. Endosome. S-nitrosylated form recycled in endosomes. Localizes to CAV1-containing vesicles close to the cell surface. Cleavage of heparan sulfate side chains takes place mainly in late endosomes. Associates with both forms of PRNP in lipid rafts. Colocalizes with APP in perinuclear compartments and with CP in intracellular compartments. Associates with fibrillar APP amyloid-beta peptides in lipid rafts in Alzheimer disease brains.; [Secreted glypican-1]: Secreted, extracellular space.
Brain,Colon,Lung fibroblast,Salivary gland,
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