function:May have a function in cell adhesion and/or receptor signaling.,PTM:N-glycosylated.,similarity:Contains 1 fibronectin type-III domain.,similarity:Contains 10 LRR (leucine-rich) repeats.,tissue specificity:Expressed in kidney and brain.,
Cell membrane ; Single-pass membrane protein . Endoplasmic reticulum membrane . Cytoplasmic vesicle membrane . Cytoplasm, perinuclear region . Cell junction, focal adhesion . Secreted . Cell projection, neuron projection . Cell junction . In addition to its location at the cell membrane, colocalizes with FGFR1 in punctate perinuclear cytoplasmic vesicles. Detected along neurites and at contacts between neurite termini and other cells. Proteolytic cleavage gives rise to a shedded ectodomain. .
Expressed in kidney and brain.