function:Promotes guanine-nucleotide exchange on ARF1 and ARF5. Promotes the activation of ARF through replacement of GDP with GTP.,similarity:Contains 1 PH domain.,similarity:Contains 1 SEC7 domain.,subunit:Interacts with TRIM23 and CYTIP.,tissue specificity:Ubiquitous.,
Cell membrane ; Peripheral membrane protein . Cytoplasm, cytosol . Cell junction, tight junction . Cell junction, adherens junction . Colocalized with TJP1 during epithelial polarization. .
Ubiquitous.
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