function:May inhibit NODAL and BMP signaling during neural patterning (By similarity). May be a tumor suppressor in brain cancers.,similarity:Belongs to the tomoregulin family.,similarity:Belongs to the UPF0439 family.,similarity:Contains 1 EGF-like domain.,similarity:Contains 2 Kazal-like domains.,subunit:May interact with ST14.,tissue specificity:Expressed in brain.,tissue specificity:Expressed predominantly in brain, and at lower levels in heart, placenta and skeletal muscle. Down-regulated in brain tumors as compared to control brain tissues.,
Cell membrane ; Single-pass type I membrane protein .
Expressed predominantly in brain, and at lower levels in heart, placenta and skeletal muscle. Down-regulated in brain tumors as compared to control brain tissues.
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