function:Acts as a scavenger receptor for acetylated low density lipoprotein. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. When inhibited in endothelial tube formation assays, there is a marked decrease in cell-cell interactions, suggesting a role in angiogenesis. Involved in the delivery of newly synthesized CHID1/SI-CLP from the biosynthetic compartment to the endosomal/lysosomal system.,similarity:Contains 1 Link domain.,similarity:Contains 16 EGF-like domains.,similarity:Contains 2 laminin EGF-like domains.,similarity:Contains 7 FAS1 domains.,subunit:Interacts with CHID1.,tissue specificity:High levels found in spleen, lymph node, liver and placenta. Also expressed in endothelial cells.,
Membrane ; Single-pass type I membrane protein .
High levels found in spleen, lymph node, liver and placenta. Also expressed in endothelial cells.