catalytic activity:Peptidylproline (omega=180) = peptidylproline (omega=0).,enzyme regulation:Inhibited by FK506 but not cyclosporin.,function:Interacts with functionally mature heterooligomeric progesterone receptor complexes along with HSP90 and TEBP.,induction:By androgen.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the FKBP-type PPIase family.,similarity:Contains 2 PPIase FKBP-type domains.,similarity:Contains 3 TPR repeats.,subunit:Part of a heteromultimeric cytoplasmic complex with HSP90, HSP70 and steroid receptors. Dissociates from the complex when NR3C1 binds glucocorticoid.,tissue specificity:Widely expressed, enriched in testis compared to other tissues.,
Cytoplasm . Nucleus .
Widely expressed, enriched in testis compared to other tissues.
下载说明书
