catalytic activity:NAD(+) + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor.,function:Enhances STAT6-dependent transcription (By similarity). Has ADP-ribosyltransferase activity.,similarity:Contains 1 PARP catalytic domain.,similarity:Contains 1 WWE domain.,similarity:Contains 3 Macro domains.,subcellular location:In steady state cells the protein is mostly nuclear. A minor proportion is detected in the cytoplasm.,subunit:Interacts with STAT6.,
Nucleus . Cytoplasm . In steady state splenocytes the protein is mostly nuclear (By similarity). A minor proportion is detected in the cytoplasm (By similarity). In macrophages, mainly localizes to the cytoplasm (PubMed:27796300). .
Expressed in macrophages.
下载说明书
