function:May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression.,induction:In monocytes, down-regulated by the cell-wall fraction of Mycobacterium bovis (BCG-CWS).,subcellular location:Associated with CD180 at the cell surface.,subunit:Binds CD180.,tissue specificity:Highly expressed in B-cells, monocytes and tonsil.,
Secreted, extracellular space. Associated with CD180 at the cell surface.
Highly expressed in B-cells, monocytes and tonsil.
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